alifpharma

Bactropen Ointment

Product Code: 1035

TK : 140 (1 Tube)


COMPOSITION
Each gram of ointment contains Mupirocin USP 20 mg.
PHARMACOLOGY
Mupirocin is a naturally occurring antibiotic. This antibacterial agent is
produced by fermentation using the organism Pseudomonas
fluorescens. It is active against a wide range of bacteria (e.g.
Staphylococcus aureus including methicillin-resistant strains and
Streptococcus pyogenes) those responsible for the majority of skin
infections. It is also active against gram-negative pathogens, such as
Escherichia coli and Haemophilus influenzae. Mupirocin inhibits
bacterial protein synthesis by reversibly and specifically binding to
bacterial isoleucyl transfer-RNA synthetase.
INDICATION
Bactropen ointment is indicated for the topical treatment of impetigo
(skin diseases) due to Staphylococcus aureus and Streptococcus
pyogenes. It is also indicated in folliculitis, furunculosis.
DOSAGE AND ADMINISTRATION
A small amount of Bactropen ointment should be applied to the
affected area 3 times daily for up to 10 days.
CONTRAINDICATION
The drug is contraindicated in individuals with a history of
hypersensitivity reactions to Mupirocin or any of the components of the
preparation.
WARNING AND PRECAUTION
Bactropen ointment is not for ophthalmic or intra-nasal use. As with
other antibacterial products, prolonged use may result in overgrowth of
non-susceptible organisms, including fungi. When Bactropen is used on
the face care should be taken to avoid the eyes. This is not suitable in
conjunction with cannulae and at the site of central venous cannulation.
In the event of a sensitization or severe local irritation from Bactropen
ointment, usage should be discontinued and appropriate alternative
therapy for the infection instituted. Mixing of Mupirocin ointment with
other preparations causes risk of dilution, resulting in a reduction of the
antibacterial activity and potential loss of stability of the Mupirocin in the
ointment.
SIDE EFFECTS
Reported side effects are burning, stinging or pain, itching and some
patient may be suffered rash, nausea, erythema, dry skin, tenderness,
swelling, contact dermatitis and increased exudate.
USE IN PREGNANCY AND LACTATION
Reproduction studies on Mupirocin ointment in animals have revealed
no evidence of harm to the foetus. As there is no clinical experience on
it,s use during pregnancy, Mupirocin ointment should only be used in
pregnancy when the potential benefits outweigh the possible risks of
treatment.
It is unknown whether this drug is excreted in human milk. Because
many drugs are excreted in human milk, caution should be exercised
when Mupirocin ointment is administered to a nursing woman.
USE IN CHILDREN & ADOLESCENTS
The safety and effectiveness of Mupirocin ointment have been
established in the age range of 2 months to 16 years.
DRUG INTERACTION
No drug interaction has been identified with Mupirocin ointment.
OVERDOSE
There is currently limited data with overdose of Mupirocin ointment. In
the event of overdose, the patient should be treated supportively with
appropriate monitoring as necessary.
STORAGE
Keep below 25o
C temperature, protected from light and moisture. Do
not keep in freeze. Keep out of the reach of children.
HOW SUPPLIED
Each box contains a tube of 10 gm Bactropen ointment.

Brand: NIPRO JMI Pharma Ltd


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