Palonosetron is a 2nd generation 5-HT3 receptor rcannist It is used as an antiemetic agent
Acute nausea and vomiting associated with moderately emetogenic cancer chemotherapy, acute nausea and vomiting associated with radiotherapy, postoperative nausea and vomiting g (PONV) for up to 24 hours following surgery
Mode of Action:
alosetron is a 5-HTs receptor antagonist nb a5-HT affinity for this receptor which may lead to block the vomiting signal to vomiting center and little or no for after receptors.
Brand: Opsonin Pharma Limited